Opioid Antagonists and Autism

Opioid antagonists are morphine-like substances which can be used to block the effect of endorphins in our central nervous system. Endorphins are the substances in our bodies which produce 'highs' in mood, such as when we exercise vigorously.

  • Naltrexone is an opioid antagonist used to treat conditions such as alcohol dependence and opioid dependence.
  • Naloxone is an opioid antagonist used to counter the effects of opioid overdose.

Some people believe that naltrexone can be used with some individuals with autism spectrum disorders to reduce behaviours such as self injury, hyperactivity and ritualistic behaviour.

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16 Jun 2018