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Tetrahydrobiopterin (also known as THB or BH4) is a naturally occurring nutrient and essential cofactor of the three aromatic amino acid hydroxylase enzymes.

Sapropterin is a specific form of tetrahydrobiopterin that is sold under a variety of brand names including Kuvan. It helps to activate phenylalanine hydroxylase, the enzyme that breaks down phenylalanine in the body.

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This glossary is designed to explain some of the jargon and gobbledygook used by some people when they talk about autism or research..

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