An endorphin is natural chemical which acts as a neurotransmitter, pain killer and sedative.
Endorphins are peptides - amino acid chains that are shorter than proteins - and are manufactured in the brain, spinal cord, and other parts of the body.
Opioid antagonists - such as nalorphine, naltrexone and naloxone - are morphine-like substances which can be used to block the effect of endorphins in the central nervous system.
Some people believe that opioid antagonists can be used to reduce behaviours such as self injury, hyperactivity and ritualistic behaviour in individuals with autism.
This glossary is designed to explain some of the jargon and gobbledygook used by some people when they talk about autism or research..
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The fact that an intervention is listed in this glossary does not necessarily mean that we agree with its use. Nor does it necessarily mean that there is any scientifically valid or reliable evidence behind it.