There is very strong research evidence to suggest that some atypical antipsychotics (such as aripiprazole and risperidone) may be beneficial for the treatment of aggression, irritability, hyperactivity, self injury, and repetitive behaviour in some children and adults on the autism spectrum.
There is very little high quality research evidence on the effectiveness of most other antipsychotics as a treatment for people on the autism spectrum.
There is evidence of significant side effects of some antipsychotics in some children/adults on the autism spectrum. Those side effects may include weight gain, hyperprolactinaemia (raised prolactin levels) and tachycardia (abnormally fast heart rate).
Future research should
Further research is also required to fully evaluate the role of antipsychotics in managing challenging behaviour in people with autism. Such research should include comparative studies to determine which antipsychotics are most effective for the treatment of which issues and in which individuals on the autism spectrum