There are no known adverse effects of cognitive behavioural therapy for people on the autism spectrum.
There are no known contraindications (something which makes a particular treatment or procedure potentially inadvisable) for CBT for people on the autism spectrum. However, some authors have suggested that CBT may be less effective in people on the autism spectrum. For example, Scattone and Mong (2013) suggested
“There are several potential barriers limiting the effectiveness of CBT for this population, including difficulty regulating emotions, communication deficits (e.g., comprehension, literal interpretation), motivation, cognitive inflexibility, concrete thinking, executive function deficits, therapeutic generalization across settings, and ToM deficits”