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Vitamin B6, Magnesium and Autism Ranking: Insufficient/Mixed evidence

Aims and Claims

Aims

Some people think that taking vitamin B6 with or without magnesium may help children and young people on the autism spectrum overcome a variety of problems, such as difficulties with social communication and social interaction.

Claims 

There have been various claims made for the use of vitamin B6 and magnesium supplements as an intervention for children and young people on the autism spectrum. For example, 

  • Barthélémy et al, 1981 claimed vitamin B6 supplements combined with magnesium produced improvements in social interaction and social communication, as well as improvements in reactions to the environment, in 21 children on the autism spectrum aged three to sixteen.
  • Kuriyama, S. et al, 2002 claimed that vitamin B6 supplements produced a significant increase in verbal IQ scores in 4 children on the autism spectrum aged six to 17.
  • Menage et al, 1992 claimed that vitamin B6 supplements combined with magnesium produced improvement in “…certain autistic symptoms (lack of interest in people, abnormal eye contact, impairment in verbal and non-verbal communication)” in five boys on the autism spectrum aged four to seven.
Updated
21 Dec 2018
Last Review
01 Dec 2018
Next Review
01 Dec 2021